What Is Histamine? It is a substance your cells produce to help your immune system respond to allergy triggers. It is one of the reasons why people use antihistamines to treat allergy symptoms. The highest number of histamines in your body are in your lungs, mast cells and basophils.

What Is Histamine? iStock-photo credit: Anna Bergbauer
Histamine is looked as a mediator in the process of inflammatory triggers like injuries or allergic substances. Some of the more common symptoms of high histamine levels are fatigue, dizziness, anxiety, migraine, high blood pressure, dizziness, abdominal pain, diarrhea, bloating, nasal congestion, etc.
Some of the common things that can trigger histamine are dust, air pollution, dehydration, air chemicals, etc. And some of the foods that trigger histamine are beans, bananas, chocolate, peanuts, tomatoes, walnuts, cashews, etc.
Some other triggers also called histamine liberators are wine, fish canned food, pickled vegetables, fermented cheeses, etc.
The different ways to clear histamine from your body is the following:
- Epinephrine– This hormone prevents your airways from closing if you have a severe immune response.
- Corticosteroids– It helps reduce inflammation with regards to skin or a respiratory tract.
- Supplementation– Supplement B6 and B7 to help balance out histamine levels in the body.
- H1 antihistamines– This can help trigger allergy symptoms such as dust.
- H2 antihistamines– This can help reduce stomach acid production involved in GI tract symptoms.
If you have any of the following symptoms above such as brain fog, severe headaches then you may want to contact your doctor.
The Bottom Line is histamine, a substance your cells produce to help your immune system respond to allergy triggers. It is looked as a mediator in the process of inflammatory triggers like injuries or allergic substances.
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References
- Zhao Y, Zhang X, Jin H, Chen L, Ji J, Zhang Z. Histamine Intolerance-A Kind of Pseudoallergic Reaction. Biomolecules. 2022 Mar 15;12(3):454. doi: 10.3390/biom12030454. PMID: 35327646; PMCID: PMC8945898.
- Kim KB, Kwak YS. Dehydration affects exercise-induced asthma and anaphylaxis. J Exerc Rehabil. 2019 Oct 28;15(5):647-650. doi: 10.12965/jer.1938470.235. PMID: 31723551; PMCID: PMC6834710.
- Shulpekova YO, Nechaev VM, Popova IR, Deeva TA, Kopylov AT, Malsagova KA, Kaysheva AL, Ivashkin VT. Food Intolerance: The Role of Histamine. Nutrients. 2021 Sep 15;13(9):3207. doi: 10.3390/nu13093207. PMID: 34579083; PMCID: PMC8469513.


